John Caulfield, cofounder and diplomatic advisor of the Innovadores Foundation. John Caulfield, cofounder and diplomatic advisor of the Innovadores Foundation.

HAVANA—Cuba is now emerging from some 58 years of orthodox Communist control. With that comes the inevitable question of what role American business and entrepreneurship might play in its re-development. The largest and most strategically located island in the increasingly important Caribbean/Latin American basin, Cuba could emerge quickly as the biggest international greenfield opportunity since China.