The largest of those transactions is a renewal for just under20,000 sf at 38 Sidney St., part of the 27-acre University Park atMIT mixed-use complex in Central Square. Ore Pharmaceuticals,formerly Gene Logic, is engaged in repositioning clinical-stagedrugs that have stalled in development. Forest City Enterprises isthe owner of University Park, which features 1.5 million sf ofresearch space. The landlord was represented by Meredith & GrewEVP Joseph Flaherty and VP Tucker Hansen.

The remaining three companies each committed to slightly morethan 10,000 sf, led by IntelligentMD leasing 10,750 sf at 19Blackstone St. Joule Biotechnologies is right behind in snagging10,500 sf at 83 Rogers St. in the emerging Life Science Square, andAileron Therapeutics is subleasing 10,100 sf at 840 Memorial Dr.,also known as the Riverside Technology Center.

"These exciting, young companies are reflective of the activitywe are seeing in Cambridge," says Cushman & Wakefield executivedirector Mark Winters, who brokered all four deals on behalf of thetenants along with colleagues Juliette Reiter and DavidTownsend.