Investment models can be useful. The usual split between medical office and life sciences is an example. Life science is R&D and product development. Medical office, tied in with hospitals, is essentially the retail side, providing care close to where people live.

Fundamental differences express themselves through specifics of ideal locations, property and facilities requirements, HVAC needs, equipment, staffing, tenant sizes, revenue sources, longevity, support systems, and even parking. Those basics help investors focus and specialize.

But the same models can leave investors behind when hybrids appear. An example is the medical research center that Weill Cornell Medicine opened last November at 1334 York Avenue, taking five floors of the Sotheby's auction house.

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