SAN DIEGO—An affiliate of Oak Coast Properties purchased the 219 room hotel in a deal arranged by CBRE Hotels of Newport Beach.

CAMBRIDGE, MA—RNAi Pioneer will ultimately take all of 675 West Kendall laboratory and office building to accommodate its growing R&D efforts.

IRVINE, CA—The 262,463-square-foot corporate headquarters building at 9950 Jeronimo Road in Irvine will undergo a $20 million re-design.

SAN DIEGO—Invesco-Cruzan partnership will pay just over $85 million for a 311,000 square foot space in a deal brokered by CBRE.

CAMBRIDGE, MA—Biogen expansion has pushed BioMed Realty's 301 Binney St. property to 100% occupied.

SAN DIEGO—Matthew Bateman is now leading the company's asset management and property management teams as chief operating officer.

SAN DIEGO—The site is near two other projects under development by the buyer HG Fenton Property Co.

IRVINE, CA—Housing data firm says that price appreciation in February was slowed compared to February 2014 in more than half of the markets analyzed.