CHICAGO—The neighborhood has not seen new apartment construction since the 1970s, but Guggenheim Real Estate and several partners are ready to rebuild its Medical District Apartments into a mixed-use community.

COLUMBUS—This city has developed nearly 200 acres of new parkland in its core area, and made it into a destination for younger residents.

BALTIMORE—This is the company's second major acquisition this year, following plans to purchase five Mars Super Markets in Baltimore.

MIAMI—“No market is completely immune to fluctuation.”