Demand from various industries has pushed gross activity and rents up and vacancy down, and there has been an uptick in rollover from adjacent regions such as Orange County, where the market is even tighter, CBRE's Tom McAllister tells GlobeSt.com.

Like many coastal cities, San Diego has lots of small residential properties that represent the vast majority of rental housing in the market, Sunrise Management's Phil Smith tells GlobeSt.com.

The Spectrum 4 project will replace an existing two-story building with a new 171,000-square-foot, three-story office/lab building, creating a world-class R&D facility for Vertex Pharmaceuticals here, LPA Inc.'s Eric Jones tells GlobeSt.com.

Buying right is about seeing what others don't and being unafraid to be a contrarian; using relationships to capture off-market deal flow and capitalize on the still-inefficient nature of real estate—and more, Cress Capital's Ryan Parkin tells GlobeSt.com.

Kearny Mesa is particularly attractive due to its diverse range of industries, which provides a sense of stability to investors since the region is less likely to be impacted by shifts in one industry, BLT Enterprises' Bernard Huberman tells GlobeSt.com.

The design and layout need to accommodate incoming and outgoing customers, with sensitivities for the many types of visitors—some may be adopting an animal, while others are anxious to pick up a lost pet, C.W. Driver's Andy Feth tells GlobeSt.com.

The second Walgreens to trade in San Diego County in the last year represents buyers' appetite for single-tenant retail assets with long-term leases and national tenants in good areas, HIG's Kevin Fryman tells GlobeSt.com EXCLUSIVELY.

Loan-estimate documents with the addresses of the desired properties can indicate show which markets are trending and likely to be strong with lots of sales activity going forward, ATTOM Data's Daren Blomquist tells GlobeSt.com.